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Liver-sparing operation associated with higher survival rates in cancer patients

Historically, the most common surgical method of treatment for liver cancer was a major hepatectomy in which a lobe (hemi-liver) is removed in order to remove the tumor. ...

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Study sheds new light on asthma, COPD

"The new study lays the groundwork for developing treatments for diseases such as asthma, COPD, cystic fibrosis and even certain cancers," said senior author Thomas J. Brett, PhD, assistant professor...

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Precision medicine for adrenal cancer, study suggests

In a randomized phase 3 trial, adrenal cancer patients receiving the investigational drug linsitinib fared no better than patients receiving a placebo. But the researchers noticed a small subset of...

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New therapeutic target may improve treatment for brain cancer

The research will be presented at the American Society for Pharmacology and Experimental Therapeutics (ASPET) Annual Meeting during Experimental Biology 2015. Monteagudo's research indicates a new...

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Women with ovarian cancer gain extra months with addition of drug to standard...

The preliminary findings were reported here at the Society of Gynecologic Oncology's Annual Meeting on Women's Cancer. The phase III, randomized, controlled trial included women with platinum-sensitive...

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Most women with early-stage breast cancer avoid extensive lymph node removal

Until now, it was unclear to what extent surgeons were following the recommendations of a landmark clinical trial published more than four years ago, known as the American College of Surgeons Oncology...

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Golgi trafficking controlled by G-proteins

The study is reported online April 9 in Developmental Cell. "Our work provides the first direct evidence that G proteins are signaling on membranes inside cells, not just at the cell surface as has...

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Stem cell disease model clarifies bone cancer trigger

The study results, published in the journal Cell, revolve around iPSCs, which since their 2006 discovery have enabled researchers to coax mature (fully differentiated) bodily cells (e.g. skin cells) to...

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Axillary lymph node evaluation performed frequently in ductal carcinoma in situ

While axillary lymph node evaluation is the standard of care in the surgical management of invasive breast cancer, a benefit has not been demonstrated in ductal carcinoma in situ (DCIS). For women with...

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Epigenomic changes play an important role during the progression of melanoma

Human DNA contains genetic information that makes our cells functional entities within a larger whole. The stream of information from DNA to function happens in the form of proteins that anchor...

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